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Measurement of Diamine Oxidase Activity in Vaginal Fluid – An Aid to Diagnosis of Ruptured Fetal Membranes
Author(s) -
Wishart M. M.,
Jenkins D. T.,
Knott M. L.
Publication year - 1979
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1979.tb01345.x
Subject(s) - membrane , diamine oxidase , medicine , fetus , rupture of membranes , chromatography , chemistry , pregnancy , biochemistry , biology , enzyme , genetics
Summary: Measurement of diamine oxidase (DAO) activity in vaginal fluid as an aid to diagnosis of premature rupture of the fetal membranes was studied. In 76 patients following artificial rupture of the membranes and in 70 patients with known intact membranes, the accuracy was 100%. One hundred and forty‐nine patients were admitted to hospital with suspected ruptured membranes; using the criteria outlined in this paper, 51 had ruptured membranes and in 98 the membranes were intact. The overall accuracy was 96%.