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Evaluation of a Sensitive Beta Subunit H.C.G. Haemagglutination Assay as a Pregnancy Test
Author(s) -
Killip M.
Publication year - 1978
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1978.tb00030.x
Subject(s) - pregnancy test , pregnancy , hemagglutination , medicine , beta (programming language) , test (biology) , protein subunit , chemistry , immunology , biology , antibody , biochemistry , genetics , paleontology , gene , computer science , programming language
Summary: A new test for the detection of the beta subunit of human chorionic gonadotrophin (HCG) was used to test urine samples from 80 patients in whom pregnancy was suspected and who had given a negative result with a routine slide pregnancy test. The samples were also tested with Higonavis, a haemagglutination test for HCG, at a level of 500 iu/l. The beta subunit test was correctly positive in 18/21 patients (86%) and correctly negative in 57/59 (97%). The respective figures for the Higonavis test were 15/21 (71%) and 59/59. The sensitivity of the beta subunit test (100 iu/l) and cross‐reaction with LH (10%), as indicated by the manufacturer, were confirmed.