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Serum Heat Stable Alkaline Phosphatase Compared with Urinary Oestriol in Abnormal Pregnancy
Author(s) -
Ward Humphry,
Whyley G. A.,
Fricker E. S. A.,
Stolen A. E.
Publication year - 1973
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1973.tb02273.x
Subject(s) - urinary system , alkaline phosphatase , fetal distress , pregnancy , obstetrics , medicine , fetus , gynecology , physiology , andrology , endocrinology , chemistry , biology , enzyme , biochemistry , genetics
Summary: Three hundred and one estimations of serum heat stable alkaline phosphatase were made in 46 normal pregnancies to obtain mean values and a range between 22 weeks and term. One hundred and twelve patients with complications of pregnancies had 674 serial serum HSAP assays and 586 urinary oestriol estimations performed. Serum HSAP levels alone or those expressed as a percentage of the total alkaline phosphatase were found to be of little or no value in monitoring the fetal welfare in high risk pregnancies or in predicting stillbirth or neonatal death. Serial urinary oestriol estimations were abnormal in 83% of pregnancies complicated by intra‐uterine fetal growth retardation and in 88% of these pregnancies if fetal distress had occurred.