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The Investigation and Treatment of Patients with Ovulation Failure: with Special Reference to the Problems Arising with the use of Clomiphene
Author(s) -
Schokman F. C. M.,
Correy J. F.,
Cusick E. T.
Publication year - 1971
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1971.tb00486.x
Subject(s) - ovulation , anovulation , medicine , pregnancy , gynecology , induced ovulation , placebo , ovulation induction , endocrine system , obstetrics , hormone , biology , alternative medicine , insulin resistance , polycystic ovary , pathology , insulin , genetics
Summary An analysis has been made of the results of investigation and treatment of patients with anovulation and oligo‐ovulation who attended a gynaecological endocrine clinic. This has revealed the need for a careful evaluation of the parameters for detecting ovulation and demonstrates the fallacy of using a single parameter as an indicator of ovulation. A scheme of management is proposed which takes into account the value of treatment with placebo and cyclic hormone therapy and which may help to elucidate the problem of failure to achieve pregnancy when the use of clomiphene followed by HCG has presumably resulted in ovulation.