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The Process of Cervical Regeneration After Electrocauterization:Part 1. Histological and Colposcopic Study
Author(s) -
Reid Bevan L.,
Singer Albert,
Coppleson Malcolm
Publication year - 1967
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1967.tb01619.x
Subject(s) - stratified squamous epithelium , peripheral blood mononuclear cell , epithelium , regeneration (biology) , pathology , cervix , colposcopy , columnar cell , medicine , staining , anatomy , chemistry , biology , microbiology and biotechnology , cervical cancer , in vitro , biochemistry , cancer
summary A combined colposcopic and histological study was made of the early phase of the healing of therapeutic electrocautery burns to the cervix. Studies at days 2–3 after burning showed that there were no surviving cells down to a depth of 5 mm. At days 3–4 nerve axones and mononuclear cells appeared in the necrotic scaffold. At days 7–10 the appearances suggested that mononuclear cells commenced to differentiate into cells of the following morphological types: squamous cells producing a stratified squamous epithelium, columnar cells producing a mucin‐secreting epithelium, fibroblasts producing collagen, and plasma cells. The contribution of the marginal healthy squamous epithelium to the re‐epithelialising process was identifiable in the period studied and consisted of a very small peripheral margin. The early appearance of ribonucleoprotein‐loaded axones and their intimate association with the mononuclear cells is discussed.