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Experimental Foetal Bradycardia during Postmaturity in the Rabbit
Author(s) -
Martin J. D.,
Young Maureen
Publication year - 1963
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1963.tb00216.x
Subject(s) - bradycardia , in utero , fetus , gestation , pregnancy , medicine , gestational age , endocrinology , fetal circulation , placenta , heart rate , biology , blood pressure , genetics
Summary:1 Relatively large doses of adrenaline given intravenously to the maternal rabbit from the 25th day to the 30th day (term) of pregnancy, produced a transient bradycardia in the foetus. There was no increased sensitivity of the utero‐placental circulation to vasoconstrictors with advancing gestational age. 2 The injection of progesterone and chorionic gonadotrophin to the mother tended to increase the sensitivity of the uteroplacental vessels to adrenaline during four days of postmaturity but care is needed in the interpretation of these results. 3 The response of the foetal heart to low oxygen tensions was unaltered from the 25th‐34th days of gestation.