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The Role of the Adrenal Cortex in the Stein‐Leventhal Syndrome*
Author(s) -
Shearman Rodney P.
Publication year - 1961
Publication title -
australian and new zealand journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 65
eISSN - 1479-828X
pISSN - 0004-8666
DOI - 10.1111/j.1479-828x.1961.tb00538.x
Subject(s) - stein leventhal syndrome , adrenal cortex , cortex (anatomy) , medicine , endocrinology , urine , mania , psychology , neuroscience , bipolar disorder , lithium (medication)
Summary Evidence suggesting that the adrenal cortex is involved in the Stein‐Leventhal syndrome is examined. These patients show abnormalities on fractionation of total 17‐ketosteroids and pregnanetriolone has been detected in the urine of 16 consecutive cases. As this steroid has been previously detected only in patients with gross adrenal dysfunction it is felt that this provides additional support for the thesis that the adrenal cortex plays a role in the Stein‐Leventhal syndrome.