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Novel environmentally benign procedure for the synthesis of 2‐aryl‐ and 2‐hetaryl‐4(3 H )‐quinazolinones
Author(s) -
Deligeorgiev T G,
Kaloyanova St,
Vasilev A,
Vaquero JJ,
AlvarezBuilla J,
Cuadro Ana M
Publication year - 2010
Publication title -
coloration technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.297
H-Index - 49
eISSN - 1478-4408
pISSN - 1472-3581
DOI - 10.1111/j.1478-4408.2010.00223.x
Subject(s) - polyethylene glycol , condensation , microwave irradiation , aryl , chemistry , environmentally friendly , combinatorial chemistry , condensation reaction , organic chemistry , alkyl , ecology , physics , biology , thermodynamics , catalysis
A novel environmentally benign procedure for the synthesis of 2‐aryl‐ or 2‐hetaryl‐4(3 H )‐quinazolinones by condensation of anthranilamide with various aromatic aldehydes in polyethylene glycol under microwave irradiation has been developed. In contrast with other reported methods, this procedure provides the corresponding quinazolinones with good to high yields and purity, in very short reaction times and without the use of an oxidant.