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Extragastric Manifestations of Helicobacter pylori Infection – Other Helicobacter Species
Author(s) -
Solnick Jay V.,
Franceschi Francesco,
Roccarina D.,
Gasbarrini Antonio
Publication year - 2006
Publication title -
helicobacter
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 79
eISSN - 1523-5378
pISSN - 1083-4389
DOI - 10.1111/j.1478-405x.2006.00430.x
Subject(s) - helicobacter , helicobacter pylori , disease , helicobacter pylori infection , immunology , biology , inflammatory bowel disease , medicine , gastroenterology
Abstract Recent studies have indicated a strong link between Helicobacter pylori and idiopathic thrombocytopenic purpura and iron deficiency anemia. Interesting results have also been obtained for ischemic heart disease, though most putative associations between H. pylori infection and extragastric disease remain speculative. With regard to other Helicobacter species, Helicobacter felis has been shown to play a role in gastric carcinogenesis in mouse models. An increased susceptibility to cholesterol gallstone formation has been described in animals fed a lithogenic diet and infected with Helicobacter bilis , or co‐infected with Helicobacter hepaticus and Helicobacter rodentium. Finally, enterohepatic Helicobacter species have also been exploited to better understand inflammatory bowel disease.