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Black pigments in the liver related to gold and titanium deposits. a report of four cases
Author(s) -
Brenard R.,
Dumortier P.,
Del Natale M.,
Honhon B.,
Van Den Berghe M.,
Bataille C.,
Rickaert F.,
Henrion J.,
Peny M. O.,
Rahier J.
Publication year - 2007
Publication title -
liver international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.873
H-Index - 110
eISSN - 1478-3231
pISSN - 1478-3223
DOI - 10.1111/j.1478-3231.2006.01431.x
Subject(s) - titanium , gold standard (test) , pigment , cholestasis , medicine , pathology , materials science , chemistry , metallurgy , gastroenterology , organic chemistry
Black pigments are rarely described in the liver. We report four patients with chronic cholestasis and black pigments described on liver histological examination. Energy‐dispersive X‐ray analysis identified these black pigments as gold particles in the first three patients and titanium particles in the fourth. The origin of the gold deposits was unknown in this first patient and related to gold salts therapy in the two others. Titanium deposits was associated with hepatic granulomas and related to total knee replacement.