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Histopathological and immunohistochemical studies of apocrine sweat gland adenocarcinomas in cats
Author(s) -
Haziroglu R.,
Haligur M.,
Keles H.
Publication year - 2014
Publication title -
veterinary and comparative oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 34
eISSN - 1476-5829
pISSN - 1476-5810
DOI - 10.1111/j.1476-5829.2012.00321.x
Subject(s) - pathology , apocrine , cytokeratin , immunohistochemistry , stroma , carcinoembryonic antigen , vimentin , cuboidal cell , sweat gland , cyst , stromal cell , biology , medicine , anatomy , sweat , cancer
Seven adenocarcinomas of apocrine sweat glands among the 67cutaneous tumours of cats were evaluated between 1980 and 2005. Histopathologically, three tumours were solid, tubular, tubular‐ductal, tubular‐cystic and papillar‐cystic types were also diagnosed each one. Cuboidal and squamous epithelial cells surrounding the cystic lumina and their papillar extensions into the cyst lumens were evident in almost all tumour types. Besides, fibrovascular stroma which surrounding neoplastic foci showed proliferation and stromal invasion. Immunohistochemical features of these tumours were examined with pan‐cytokeratin, vimentin and carcinoembryonic antigen.