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Mitochondria as pharmacological targets
Author(s) -
Moncada S
Publication year - 2010
Publication title -
british journal of pharmacology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.2010.00706.x
Subject(s) - mitochondrion , clinical pharmacology , pharmacology , identification (biology) , drug action , action (physics) , medicine , drug , neuroscience , bioinformatics , biology , microbiology and biotechnology , botany , physics , quantum mechanics
In the last decade, mitochondria have provided a vast area of research for the pharmacologist, with a wealth of potential targets for drug action. Correct target identification and subsequent pharmacological manipulation might greatly help in the prevention and/or treatment of a number of the most prevalent diseases of our time including cancer, neurodegenerative disease and myocardial infarction. This is a commentary to accompany the publication of three papers in this issue of the BJP by Kurz et al., Pravdic et al. and Puerta et al. on different aspects of pharmacology involving mitochondria.