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Methylxanthine‐induced attenuation of pecking in chickens
Author(s) -
Zarrindast M.R.,
Nasir T.
Publication year - 1991
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1991.tb12430.x
Subject(s) - caffeine , theophylline , apomorphine , pecking order , adenosine , adenosine receptor , endocrinology , pharmacology , chemistry , medicine , receptor , biology , agonist , evolutionary biology
1 Apomorphine induced dose‐dependent pecking in chickens. 2 The response was decreased by theophylline or caffeine in a dose‐dependent manner. 3 Administration of theophylline or caffeine alone did not exert any effect on pecking behaviour. 4 Dipyridamole administration neither induced pecking nor altered the pecking induced by apomorphine. 5 Administration of 5‐N‐ethylcarboxamide‐adenosine to animals caused variable effects on pecking induced by apomorphine. The drug did not induce pecking by itself. 6 It is concluded that the inhibitory response to methylxanthines may be mediated through blockade of adenosine receptors. However, to prove this, more experiments are needed.