Premium
Increased surface glycoconjugates of synaptic membranes in mice during chronic ethanol treatment
Author(s) -
Goldstein Dora B.,
Hungund Basalingappa L.,
Lyon Robbe C.
Publication year - 1983
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1983.tb09356.x
Subject(s) - glycoconjugate , ethanol , galactose oxidase , galactose , membrane , chemistry , sodium borohydride , biochemistry , catalysis
Synaptosomal plasma membranes from mice treated chronically with ethanol were incubated with galactose oxidase and [ 3 H]‐sodium borohydride, in order to label the exposed galactose and N‐acetylgalactosamine groups of glycoconjugates. The ethanol treatment approximately doubled the amount of exposed sugars. This change may be related to previously observed alterations in the physical properties of neuronal membranes in ethanol‐treated mice.