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EFFECTS OF PROPRANOLOL ON GASTRIC SECRETION IN ALBINO RATS
Author(s) -
DEBNATH P.K.,
GODE K.D.,
DAS D. GOVINDA,
SANYAL A.K.
Publication year - 1974
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1974.tb09649.x
Subject(s) - propranolol , pepsin , gastric secretion , secretion , medicine , gastric acid , endocrinology , pylorus , pharmacology , stomach , chemistry , biochemistry , enzyme
1 Effects of graded doses of propranolol have been studied on gastric secretion and gastric ulcers in pylorus‐ligated rats. 2 A dose‐dependent action of propranolol was observed; small doses increased total volume, acid output and pepsin secretion along with an increase in the incidence of ulcers but high doses were inhibitory.