Premium
SOME SHORTCOMINGS OF DIRECT INTRAVENTRICULAR INJECTION IN MICE
Author(s) -
SHAW G.G.
Publication year - 1974
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1974.tb08596.x
Subject(s) - leakage (economics) , labelling , neuroscience , anesthesia , medicine , chemistry , biology , biochemistry , macroeconomics , economics
The use of X‐ray photography following injection of iophendylate to verify that intraventricular injections in mice have been satisfactorily accomplished is misleading since it fails to detect leakage into the periphery. Radioactive labelling reveals that a substantial proportion of the injected material is rapidly carried to the periphery in the bloodstream.