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Frequency dependence of dual negative feedback control of secretion of sympathetic neurotransmitter in guinea‐pig vas deferens
Author(s) -
Stjärne L.
Publication year - 1973
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1973.tb08383.x
Subject(s) - vas deferens , neurotransmitter , guinea pig , endocrinology , medicine , stimulation , norepinephrine , secretion , prostaglandin e2 , adrenergic , chemistry , biology , dopamine , central nervous system , receptor
The secretion of sympathetic neurotransmitter in guinea-pig vas deferens appears to be normally controlled by two different mechanisms, one dependent and one independent of prostaglandin E. The efficiency of both control systems, as well as of exogenous prostaglandin E(2), is inversely related to nerve stimulation frequency.