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The ionic composition of aortic smooth muscle from A.S.‐hypertensive rats
Author(s) -
Massingham R.,
Shevde S.
Publication year - 1973
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1973.tb08340.x
Subject(s) - smooth muscle , medicine , philosophy
The Na(+), K(+) and Ca(2+) content of plasma and aortic vascular smooth muscle from normotensive and A.S.-hypertensive rats have been compared. There was no significant difference in the plasma concentrations of Na(+), K(+) and Ca(2+), or the Na(+), K(+) and water content or (3)H-inulin space of aortic tissue in the two groups.There was a marked increase in the amount of Ca(2+) in the aortae taken from the hypertensive animals as compared with the normotensive animals (P<0.01).