Premium
Effect of cromoglycate on anaphylactic histamine release from rat peritoneal mast cells
Author(s) -
Garland L. G.
Publication year - 1973
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1973.tb08275.x
Subject(s) - histamine , disodium cromoglycate , mast (botany) , mast cell , pharmacology , chemistry , histamine h4 receptor , medicine , immunology , histamine h2 receptor , antagonist , receptor
Cromoglycate (1-30 muM) produced a concentration-dependent inhibition of anaphylactic histamine release from actively sensitized rat peritoneal mast cells but at lower concentrations (0.01-0.1 muM) occasionally produced a concentration-dependent enhancement of histamine release.