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The distribution of lithium and its effects on the distribution and excretion of other ions in the rat
Author(s) -
BIRCH N. J.,
JENNER F. A.
Publication year - 1973
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1973.tb08189.x
Subject(s) - calcium , lithium (medication) , sodium , magnesium , endocrinology , chemistry , medicine , excretion , urine , distribution (mathematics) , biochemistry , mathematical analysis , mathematics , organic chemistry
Summary1 In rats, lithium (ca 1 mEquiv/kg body weight) decreased brain sodium and magnesium, bone sodium and calcium and increased muscle calcium, plasma magnesium, urinary calcium and urine volume. 2 Lithium was particularly concentrated in bone.