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The effect of β‐adrenoceptor blockade on human sweating
Author(s) -
ALLEN JUDITH A.,
JENKINSON D. J.,
RODDIE I. C.
Publication year - 1973
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1973.tb08180.x
Subject(s) - propranolol , atropine , blockade , mental arithmetic , anesthesia , medicine , endocrinology , psychology , blood pressure , heart rate , receptor
Summary1 Changes in cutaneous water loss were followed by continuously monitoring total body weight loss. 2 Sweating was induced in normal subjects by raising the environmental temperature or by subjecting them to the emotional stress of mental arithmetic. 3 Propranolol in a dosage of 0·15 mg/kg body weight intravenously had no significant effect on either thermal or emotional sweating, whereas thermal sweating was completely blocked temporarily by administration of atropine 2·4 mg intravenously. 4 It is concluded that β‐adrenoceptor blockade has no effect on physiological sweating in normal people.