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Actions of morphine on the segmental reflex of the decerebrate‐spinal cat
Author(s) -
KRIVOY W.,
KROEGER D.,
ZIMMERMANN E.
Publication year - 1973
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1973.tb08177.x
Subject(s) - morphine , reflex , (+) naloxone , anesthesia , decerebration , stimulation , decerebrate state , medicine , opioid , electric stimulation , receptor
Summary1 The actions of morphine were studied on the segmental reflex of the decerebrate‐spinal cat. Morphine decreased arterial blood pressure. 2 Morphine inhibited mono‐ and polysynaptic reflexes. The influence of morphine on monosynaptic reflexes was more obvious at stimulation of the dorsal root at a frequency of 12·5 Hz than at 05 or 2·5 Hz. 3 The total amount of activity recorded from the ventral root after morphine depended on whether or not the evoked reflex was maximal or submaximal. 4 These actions of morphine were antagonized by naloxone.