Premium
The anti‐inflammatory effect of catecholamines in the peritoneal cavity and hind paw of the mouse
Author(s) -
GREEN K. L.
Publication year - 1972
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1972.tb08086.x
Subject(s) - endocrinology , peritoneal cavity , medicine , hindlimb , chemistry , peritoneum , epinephrine , pharmacology , anatomy
Summary1 Carrageenin or 5‐hydroxytryptamine‐induced oedema of the mouse hind paw was antagonized by catecholamines acting on both α‐ and β‐adrenoceptors. 2 Increased permeability of the mouse peritoneum induced by the local injection of acetic acid or pro‐inflammatory mediators was antagonized by catecholamines acting predominantly on β‐adrenoceptors. 3 The anti‐inflammatory effect of catecholamines was due neither to hyper‐glycaemia nor to the release of adrenal cortical hormones.