Premium
The muscle relaxant activity of methaqualone and its methyl congener
Author(s) -
Bhargava K. P.,
Rastogi S. K.,
Sinha J. N.
Publication year - 1972
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1972.tb07318.x
Subject(s) - methaqualone , congener , muscle relaxant , chemistry , pharmacology , medicine , environmental chemistry
Studies with methaqualone and dimethylquinazolone showed them to possess both central and peripheral muscle relaxant activity, the latter only at high dose levels. They selectively inhibited polysynaptic reflexes and were more potent than mephenesin.