Premium
Cardiorespiratory effects of intravenous isoprenaline and salbutamol in dogs
Author(s) -
LOH L.,
SEED R. F.,
SYKES M. K.
Publication year - 1971
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1971.tb08042.x
Subject(s) - isoprenaline , salbutamol , cardiorespiratory fitness , medicine , anesthesia , blood pressure , heart rate , arterial oxygen tension , pulse rate , cardiac output , central venous pressure , cardiology , asthma , lung , stimulation
Summary1 The cardiorespiratory effects of intravenous infusions of isoprenaline and salbutamol (1 and 5 μg/min) have been compared in twelve dogs. 2 Both drugs produced a rise in pulse rate, a fall in systemic arterial pressure and a rise in pulmonary arterial pressure. Salbutamol produced a greater increase in cardiac output than isoprenaline. 3 Both drugs produced an increase in venous admixture, but a significant fall in arterial oxygen tension occurred only with isoprenaline at the higher dose.