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Responses to pressor substances in conscious and anaesthetized cats
Author(s) -
Owen D. A. A.
Publication year - 1971
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1971.tb07196.x
Subject(s) - pharmacy , medicine , library science , reserpine , psychology , family medicine , pharmacology , computer science
The blood pressure responses to intravenous injections of noradrenaline, tyramine and McN-A-343 have been determined in conscious cats and in cats under pentobarbitone sodium, alpha-chloralose, urethane or alpha-chloralose plus urethane anaesthesia. All four anaesthetic agents reduced the pressor responses, the reduction being most pronounced with urethane and least pronounced with alpha-chloralose. Pentobarbitone sodium exerted a greater inhibitory effect on the responses to McN-A-343 than on those to noradrenaline or tyramine.