Premium
Distribution of tritium labelled Δ 1 ‐tetrahydrocannabinol in the rat brain following intraperitoneal administration
Author(s) -
Layman J. M.,
Milton A. S.
Publication year - 1971
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1971.tb07114.x
Subject(s) - pharmacy , medicine , citation , library science , family medicine , computer science
Tritiated Delta(1)-tetrahydrocannabinol was injected intraperitoneally into rats and its distribution measured in the brain for up to 30 days after administration. The results showed that there was no selective distribution in any one area of the brain. The maximum levels of radioactivity occurred 1 h after the injection of the tetrahydrocannabinol, thereafter the levels fell very slowly, with demonstrable activity still present at the end of 30 days.