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Cardio‐selective β‐adrenoceptor blockade and the coronary circulation
Author(s) -
Adam K. R.,
Boyles Susan,
Scholfield P. C.
Publication year - 1970
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1970.tb10639.x
Subject(s) - practolol , blockade , stimulation , vasoconstriction , medicine , coronary circulation , adrenergic beta antagonists , cardiology , propranolol , receptor , blood flow
After blockade of myocardial, but not coronary vascular β‐adrenoceptors by practolol, cardiac sympathetic stimulation or exo‐genously administered noradrenaline gave rise coronary vasoconstriction, possibly due to stimulation of coronary a‐adrenoceptors.