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Tremor induced by tetrabenazine
Author(s) -
CALNE D. B.,
WEBSTER R. A.
Publication year - 1969
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1969.tb10583.x
Subject(s) - tetrabenazine , parkinsonism , cats , oxotremorine , anesthesia , shivering , medicine , hypothermia , pharmacology , muscarinic acetylcholine receptor , receptor , disease , dopamine
1 . Acute administration of tetrabenazine produced tremor in cats, in doses which caused sedation but not hypothermia. 2 . The pattern of movements resembled shivering rather than Parkinsonism, and warming the skin suppressed the tremor. 3 . The tremor was not influenced by hyoscine. 4 . Tremor produced by amylobarbitone was essentially similar to that induced by tetrabenazine.