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Intra‐hepatic vascular response to sodium nitrite
Author(s) -
GEUMEI AIDA,
ISSA I.,
MAHFOUZ M.
Publication year - 1969
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1111/j.1476-5381.1969.tb08286.x
Subject(s) - vasoconstriction , medicine , cardiology , venous return curve , liver circulation , angina , sodium nitrite , portal venous pressure , cardiac output , portal hypertension , anesthesia , blood pressure , chemistry , hemodynamics , portal vein , organic chemistry , myocardial infarction , cirrhosis
1 In the perfused liver of the dog, sodium nitrite produced vasoconstriction in the hepatic arterial bed and, particularly, in the portal venous vascular bed. 2 These effects on the hepatic vasculature may account in part for the reduction of venous return and diminution in cardiac output recorded by other workers, and may therefore be a factor in the clinical efficacy of the nitrites in angina pectoris.