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KININ‐FORMING AND DESTROYING ACTIVITIES OF SALIVA
Author(s) -
AMUNDSEN E.,
NUSTAD K.
Publication year - 1964
Publication title -
british journal of pharmacology and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0366-0826
DOI - 10.1111/j.1476-5381.1964.tb01600.x
Subject(s) - saliva , kinin , secretion , chemistry , epithelium , endocrinology , parotid gland , oral cavity , medicine , pathology , bradykinin , dentistry , receptor
Kininase activity is present in saliva obtained from the oral cavity but not in saliva obtained by cannulation of the parotid or submandibular ducts. This activity originates from squamous epithelial cells from the oral mucous membranes. Experiments with various inhibitors indicated that the kininase activity of squamous epithelial cells differs from that of plasma, and resembles that of erythrocytes. Kinin‐forming activity is present both in the glandular secretion and in the squamous epithelial cells.