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A STUDY OF POSSIBLE MEDIATORS OF INFLAMMATORY REACTIONS IN THE MOUSE FOOT
Author(s) -
NORTHOVER B. J.,
SUBRAMANIAN G.
Publication year - 1962
Publication title -
british journal of pharmacology and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0366-0826
DOI - 10.1111/j.1476-5381.1962.tb01415.x
Subject(s) - pyrazolones , chemistry , formaldehyde , pharmacology , glycoside , foot (prosody) , flavanone , medicine , biochemistry , stereochemistry , organic chemistry , flavonoid , antioxidant , linguistics , philosophy
A number of compounds have been studied for their ability to antagonize the inflammatory reaction produced by injections of formaldehyde and 5‐hydroxytryptamine in the mouse foot. An attempt has been made to elucidate the ways in which certain hydroxybenzoates, pyrazolones, sympathomimetic amines, flavone and flavanone glycosides, local anaesthetics, antihistamines and anti‐5‐hydroxytryptamine substances produce their anti‐inflammatory effect.