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HISTAMINE PROTECTION IN GUINEA‐PIGS PRODUCED BY PLANT TUMOUR EXTRACTS
Author(s) -
BROOME J.,
CALLOW R. K.,
FELDBERG W.,
KOVACS B. A.
Publication year - 1962
Publication title -
british journal of pharmacology and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0366-0826
DOI - 10.1111/j.1476-5381.1962.tb01153.x
Subject(s) - gall , histamine , guinea pig , biology , botany , traditional medicine , pharmacology , medicine , endocrinology
Stable extracts were obtained from plant tumours, such as Hungarian oak galls and crown galls of infected tomato plants, which, injected intraperitoneally into guinea‐pigs, protected the animals against a subsequent histamine aerosol. The protection produced by the oak gall extracts lasted for a few days and that produced by the crown gall extracts, if injected in sufficient amounts, sometimes for a few weeks.