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EFFECTS OF 5‐HYDROXYTRYPTAMINE ON THE DORSAL MUSCLE OF THE LEECH (HIRUDO MEDICINALIS)
Author(s) -
SCHAIN R. J.
Publication year - 1961
Publication title -
british journal of pharmacology and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0366-0826
DOI - 10.1111/j.1476-5381.1961.tb01085.x
Subject(s) - hirudo medicinalis , leech , dorsum , anatomy , biology , computer science , world wide web
5‐Hydroxytryptamine has an inhibiting effect on the leech muscle. It reduces the contractions produced by acetylcholine or nicotine and accelerates the relaxation of the muscle when these substances are washed out. This acceleration of relaxation allows a more rapid assay of acetylcholine in this preparation.