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PHARMACOLOGICAL ACTIVITY OF AN AQUEOUS EXTRACT OF THE LEAVES OF THE MALAYAN RENGAS TREE GLUTA RENGHAS
Author(s) -
LIN R. C. Y.,
WHITTOW G. C.
Publication year - 1960
Publication title -
british journal of pharmacology and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0366-0826
DOI - 10.1111/j.1476-5381.1960.tb01270.x
Subject(s) - tree (set theory) , traditional medicine , biology , chemistry , botany , medicine , mathematics , mathematical analysis
A pharmacological analysis of an aqueous extract of the leaves of Gluta renghas has been carried out. It has been shown that the extract contained a heat‐stable, anticholinesterase agent. A heart‐stimulating substance was also shown to be present in the extract. Intravenous injection of the extract into the anaesthetized cat produced changes of arterial blood pressure, venous pressure and respiration which were reduced or abolished by vagotomy. The leaves contained approximately 0.1 μg./g. of 5‐hydroxytryptamine‐like activity.