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A COMPARISON OF SOME PHARMACOLOGICAL PROPERTIES OF DIOSCORINE AND DIOSCINE
Author(s) -
BROADBENT J. L.,
SCHNIEDEN H.
Publication year - 1958
Publication title -
british journal of pharmacology and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0366-0826
DOI - 10.1111/j.1476-5381.1958.tb00893.x
Subject(s) - convulsant , analeptic , antidiuretic , chemistry , acetylcholine , pharmacology , sympathomimetics , toxicity , action (physics) , medicine , hormone , biochemistry , organic chemistry , receptor , physics , quantum mechanics
The alkaloids, dioscorine and dioscine, both obtained from yams, have been compared in respect of their convulsant activity, toxicity, analeptic action, local anaesthetic activity, adrenaline potentiating action, antidiuretic effect, and anti‐acetylcholine activity. The alkaloids have similar properties, but in most respects dioscorine was the more potent. Aqueous solutions of dioscine are unstable.