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SOME PHARMACOLOGICAL ACTIONS OF CHOLINE 2:6‐XYLYL ETHER BROMIDE
Author(s) -
WILLEY G. L.
Publication year - 1957
Publication title -
british journal of pharmacology and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0366-0826
DOI - 10.1111/j.1476-5381.1957.tb01374.x
Subject(s) - cats , nictitating membrane , blood pressure , ileum , chemistry , pharmacology , cholinergic , choline , neostigmine , muscarine , endocrinology , medicine , anesthesia , biochemistry , muscarinic acetylcholine receptor , statistics , classical conditioning , mathematics , receptor , conditioning
The following pharmacological properties of choline 2:6‐xylyl ether bromide are described: (1) nicotine‐like stimulant action on the arterial blood pressure, on the nictitating membrane, and on the soleus and gastrocnemius muscles of cats; (2) muscarine‐like action on the arterial blood pressure of cats, and on the isolated guinea‐pig ileum; (3) antihistaminic and antimuscarinic actions on the isolated guinea‐pig ileum; (4) antisympathomimetic action on the arterial blood pressure of cats; and (5) neuromuscular blocking action on skeletal muscle of cats.