Premium
THE TOXICOLOGY AND PHARMACOLOGY OF METHYL FLUOROACETATE (MFA) IN ANIMALS, WITH SOME NOTES ON EXPERIMENTAL THERAPY
Author(s) -
FOSS G. L.
Publication year - 1948
Publication title -
british journal of pharmacology and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0366-0826
DOI - 10.1111/j.1476-5381.1948.tb00362.x
Subject(s) - christian ministry , library science , medicine , faith , theology , philosophy , computer science
It has been known for about ten years that methyl fluoroacetate (MFA), CH2F.COOCH3, was a substance of great toxicity, with very interesting pharmacological properties. In 1942, Briscoe, and Feldberg, Kilby, and Kilby found that it caused death by convulsions and respiratory failure. Later in 1943, Kilby and Kilby studied it and allied substances further and concluded that the toxicity was due to the CH2F group. In this paper further work is described on its pharmacological and toxicological properties.