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Clinical, hematologic, and electrolyte changes with 0.9% sodium chloride or acetated fluids in endurance horses
Author(s) -
Fielding C. Langdon,
Gary Magdesian K.,
Meier Chloe A.,
Rhodes Diane M.
Publication year - 2012
Publication title -
journal of veterinary emergency and critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 47
eISSN - 1476-4431
pISSN - 1479-3261
DOI - 10.1111/j.1476-4431.2012.00745.x
Subject(s) - medicine , sodium , electrolyte , hyponatremia , chemistry , organic chemistry , electrode
Objective To describe the clinical and laboratory changes associated with the use of IV 0.9% sodium chloride and a commercially available acetated fluid ( CAF ) to treat endurance horses requiring emergency medical treatment. Design Randomized, controlled clinical trial from 2007 to 2010. Setting Emergency treatment centers of the Western States 100‐mile (220 km) endurance ride. Animals Twelve horses requiring emergency medical treatment in the form of IV fluids completed the study. Interventions Horses were assigned to either the 0.9% sodium chloride group (6 horses) or CAF group (6 horses) and received a total of 20 L of fluid. Clinical, hematologic, and electrolyte data were collected prior to and during fluid therapy. Measurements and Main Results As compared to results prior to fluid therapy, horses treated with 0.9% sodium chloride had a decrease in heart rate ( P < 0.01), PCV ( P < 0.001), total plasma protein (TPP) ( P < 0.001), and the sodium‐chloride difference ( P < 0.05). These horses also had an increase in plasma chloride ( P < 0.01) and sodium ( P < 0.01) concentrations. Horses treated with CAF showed a decrease in PCV ( P < 0.01) and TPP ( P < 0.001). Conclusions These findings should aid in the design a larger clinical trial to provide further clarification on the effects of type of fluid therapy on clinical and biochemical parameters in endurance horses. The use of 0.9% sodium chloride may not be ideal for the emergency management of endurance horses as it was associated with an increase in plasma chloride concentration.