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Continuous positive airway pressure administered via face mask in tranquilized dogs
Author(s) -
Briganti Angela,
Melanie Pierre,
Portela Diego,
Breghi Gloria,
Mama Khursheed
Publication year - 2010
Publication title -
journal of veterinary emergency and critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 47
eISSN - 1476-4431
pISSN - 1479-3261
DOI - 10.1111/j.1476-4431.2010.00579.x
Subject(s) - medicine , anesthesia , acepromazine , continuous positive airway pressure , blood pressure , heart rate , arterial blood , arterial catheter , oxygenation , catheter , respiratory rate , mean arterial pressure , surgery , obstructive sleep apnea
Objective– To evaluate the tolerance of a continuous positive airway pressure (CPAP) mask in tranquilized dogs and compare PaO 2 in arterial blood in dogs receiving oxygen with a regular face mask or CPAP mask set to maintain a pressure of 2.5 or 5 cm H 2 O. Design– Prospective, randomized clinical study. Setting– University teaching hospital. Animals– Sixteen client‐owned dogs without evidence of cardiopulmonary disease were studied. Interventions– Eight animals were randomly assigned to each of 2 treatment groups: group A received 2.5 cm H 2 O CPAP and group B received 5 cm H 2 O CPAP after first receiving oxygen (5 L/min) by a regular face mask. Animals were tranquilized with acepromazine 0.05 mg/kg, IV and morphine 0.2 mg/kg, IM. An arterial catheter was then placed to facilitate blood sampling for pHa, PaO 2 , and PaCO 2 determinations before and after treatments. Direct mean arterial pressure, heart rate, respiratory rate, and temperature were also recorded after each treatment. Measurements and Main Results– CPAP administration was well tolerated by all animals. The mean arterial pressure, heart rate, respiratory rate, temperature, PaCO 2 , and pHa, did not differ at any time point between groups. Differences were seen in oxygenation; in group A, PaO 2 significantly increased from a mean of 288.3±47.5 mm Hg with a standard mask to a mean of 390.3±65.5 mm Hg with the CPAP mask and in group B, PaO 2 increased similarly from 325.0±70.5 to 425.2±63.4 mm Hg ( P <0.05); no differences were detected between the 2 CPAP treatments. Conclusions– In healthy tranquilized dogs noninvasive CPAP is well tolerated and increases PaO 2 above values obtained when using a regular face mask.