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Initial Experience with Norepinephrine Infusion in Hypotensive Critically III Foals
Author(s) -
Corley Kevin,
McKenzie Harold,
Amoroso Lisa,
Furr Martin
Publication year - 2000
Publication title -
journal of veterinary emergency and critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.886
H-Index - 47
eISSN - 1476-4431
pISSN - 1479-3261
DOI - 10.1111/j.1476-4431.2000.tb00012.x
Subject(s) - norepinephrine , medicine , dobutamine , anesthesia , foal , blood pressure , resuscitation , dopamine , catecholamine , critically ill , hemodynamics , archaeology , history
Summary Seven critically ill foals that continued to be hypotensive despite fluid resuscitation and the infusion of dobutamine and/or dopamine were treated with an infusion of norepinephrine (noradrenaline). The norepinephrine was administered concurrently with dobutamine, and the combination therapy was titrated by use of indirect mean arterial pressure measurements. The highest dose of norepinephrine used was 1.5 mcg/kg/min. In six foals the administration of norepinephrine was associated with an increase in blood pressure. In one foal the mean arterial pressure did not increase in response to the doses of norepinephrine administered. All of the foals experienced an increase in urine output coincident with the start of the norepinephrine infusion. Three of the foal survived to hospital discharge.