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Joint hypermobility in keratoconus
Author(s) -
Woodward E. G.,
Morris M. T.
Publication year - 1990
Publication title -
ophthalmic and physiological optics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.147
H-Index - 66
eISSN - 1475-1313
pISSN - 0275-5408
DOI - 10.1111/j.1475-1313.1990.tb00882.x
Subject(s) - keratoconus , joint hypermobility , medicine , connective tissue , wrist , mitral valve prolapse , ehlers–danlos syndrome , hypermobility (travel) , incidence (geometry) , ophthalmology , surgery , cornea , anatomy , physical therapy , pathology , mitral valve , physics , optics
There are several reports linking keratoconus and connective tissue disorders, such as Ehlers‐Danlos syndrome, osteogenesis imperfecta and mitral valve prolapse, suggesting that keratoconus may be the result of a localized dysfunction in collagen metabolism. In view of this the incidence of hypermobility of the joints among a group of patients with keratoconus was compared with a normal (matched) control group. Eighty‐four patients were examined using the Beighton modification of the Carter and Wilkinson scoring system. A control group matched for sex, age and ethnic group was also assessed. No statistically significant difference between the groups was found for the trunk or knees; a difference was found for the metacarpo‐phalyngeal and wrist joints. The findings support the theory that keratoconus is a localized manifestation of a mild connective tissue disorder. Also, it can be stated that patients with keratoconus are five times more likely to show hypermobility of the metacarpo‐phalyngeal and wrist joints.