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The influence of contact lens wear on the corneal response to ultraviolet radiation
Author(s) -
Ahmedbhai N.,
Cullen A.P.
Publication year - 1988
Publication title -
ophthalmic and physiological optics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.147
H-Index - 66
eISSN - 1475-1313
pISSN - 0275-5408
DOI - 10.1111/j.1475-1313.1988.tb01035.x
Subject(s) - contact lens , cornea , lens (geology) , ophthalmology , irradiation , optics , effects of long term contact lens wear on the cornea , significant difference , materials science , ultraviolet radiation , medicine , chemistry , physics , nuclear physics , radiochemistry
One eye of each of 15 male pigmented rabbits was fitted with a gas‐permeable rigid contact lens. Lenses were worn on a daily basis for an initial period of 7 days with the other eye serving as a control. After this initial period the lenses were removed and both eyes were irradiated with UV‐B (305 nm ± 9 full width half maximum) using either 0.03 J cm ‐2 or 0.12 J cm ‐2 which were approximately the epithelial and endothelial damage thresholds for this waveband respectively. The responses of the cornea were followed by microscopy and pachometry. Biomicroscopically there was a dramatic difference in response between contact lens wearing and non‐wearing eyes for the higher radiant exposure, whereas little difference was observed at the lower level. For both levels of radiant exposure there was a significantly less corneal thickness increase in contact lens wearing eyes after UV‐B irradiation. Recovery patterns were similar.

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