Open AccessVertebrate aging research 2006
Author(s) -
Austad Steven N.
Publication year - 2007
Publication title -
aging cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.103
H-Index - 140
eISSN - 1474-9726
pISSN - 1474-9718
DOI - 10.1111/j.1474-9726.2007.00280.x
Subject(s) - biology , vertebrate , parade , caloric theory , fish <actinopterygii> , resveratrol , zoology , physiology , gerontology , endocrinology , pharmacology , genetics , gene , history , medicine , fishery , art history
Summary This Hot Topics review, the first in a projected annual series, discusses those articles, published in the last year, which seem likely to have a major impact on our understanding of the aging process in mammals and the links between aging and late‐life illnesses. The year's highlights include studies of oxidation damage in the very‐long‐lived naked mole‐rat, and of caloric restriction in monkeys, humans, and growth hormone‐unresponsive mice. Two studies of resveratrol, one showing its ability to extend lifespan in a short‐lived fish, the other demonstrating beneficial effects in mice subjected to a diet high in fat, may well be harbingers of a parade of intervention studies in the coming decade.