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Dermal and epidermal remodeling using botulinum toxin type A for facial, nonreducible, hyperkinetic lines: two case studies
Author(s) -
Bowler Patrick J
Publication year - 2008
Publication title -
journal of cosmetic dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.626
H-Index - 44
eISSN - 1473-2165
pISSN - 1473-2130
DOI - 10.1111/j.1473-2165.2008.00399.x
Subject(s) - forehead , medicine , dermatology , botulinum toxin , glabella , patient satisfaction , surgery
Summary Background Many studies confirm the safety and efficacy of botulinum toxin type A in a variety of clinical indications. Its use for treatment of hyperfunctional facial lines has become the most popular cosmetic procedure. These case studies comprise an evaluation of the long‐term treatment of two subjects treated with botulinum toxin type A (BOTOX®, Allergan, Irvine, CA, USA) for hyperfunctional, nonreducible, facial lines. Aims This paper aims to assess the long‐term effectiveness of BOTOX treatment for hyperfunctional facial lines in two subjects over 7 years. Patients/methods Two subjects (case 1: female aged 53 years; case 2: male age 50 years) presenting with glabelar, forehead, and periorbital facial lines were treated with BOTOX over a 7‐year period. Case 1 received a total of 24 treatments at 4‐monthly intervals, and case 2 received 21 treatments at 3‐ to 6‐monthly intervals. Results Skin quality continued to improve over time, revealing a smoother, enhanced, yet “natural” look. In particular, nonreducible forehead lines were effaced suggesting dermal and epidermal remodeling over long‐term treatment. There was no evidence of development of any new wrinkles secondary to BOTOX use, and both subjects continue to report high levels of treatment satisfaction. No safety issues were raised. Conclusions These case studies demonstrate that nonreducible horizontal forehead lines can show long‐term reduction with BOTOX treatment and high levels of subject satisfaction.