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Hallucinations treated with rivastigmine in Creutzfeldt–Jakob disease
Author(s) -
Chapuis Claire,
Casez Olivier,
Lagrange Emmeline,
Bedouch Pierrick,
Besson Gérard
Publication year - 2012
Publication title -
fundamental and clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.655
H-Index - 73
eISSN - 1472-8206
pISSN - 0767-3981
DOI - 10.1111/j.1472-8206.2011.00959.x
Subject(s) - rivastigmine , medicine , autopsy , disease , creutzfeldt jakob syndrome , neuroimaging , dementia , cerebrospinal fluid , dementia with lewy bodies , degenerative disease , pathology , psychiatry , prion protein , donepezil
Clinical features at onset of Creutzfeldt–Jakob disease (CJD) may mimic symptoms of Lewy bodies dementia. Clinical evolution, neuroimaging, metabolism exploration, and cerebrospinal fluid investigations may help establishing the diagnosis. However, CJD definite diagnosis requires postmortem autopsy. This symptom overlap led us to successfully prescribe an anticholinesterasic treatment, rivastigmine, to a patient for whom a probable CJD disease was finally diagnosed.