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The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance
Author(s) -
Catapano Alberico L.
Publication year - 2007
Publication title -
fundamental and clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.655
H-Index - 73
eISSN - 1472-8206
pISSN - 0767-3981
DOI - 10.1111/j.1472-8206.2007.00534.x
Subject(s) - balance (ability) , homeostasis , elegance , chemistry , pharmacology , medicine , endocrinology , physical therapy , philosophy , aesthetics
The recent discoveries on the concerted role of several mechanisms involved in regulating the balance of body cholesterol highlight the role of intestinal absorption. Selective modulators of intestinal cholesterol absorption are available that offer a new pharmacologic approach to the modulation of total body cholesterol homeostasis and to a more effective reduction of low‐density‐lipoprotein cholesterol.