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Salicylic acid disposition in children with rheumatoid arthritis
Author(s) -
Barzaghi N.,
Lamedica G.,
Gatti G.,
Cottafava F.,
Massocco D.,
Marchese N.
Publication year - 1991
Publication title -
fundamental and clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.655
H-Index - 73
eISSN - 1472-8206
pISSN - 0767-3981
DOI - 10.1111/j.1472-8206.1991.tb00723.x
Subject(s) - disposition , juvenile rheumatoid arthritis , rheumatoid arthritis , salicylic acid , medicine , pharmacokinetics , arthritis , juvenile , dermatology , psychology , chemistry , biology , social psychology , biochemistry , genetics
Summary— The plasma level profile of SA and SUA after a single oral dose of ASA was studied in 8 children with juvenile rheumatoid arthritis, aged 3.5–15.0 years. Pharmacokinetic parameters were on average similar to those reported in the literature for adult subjects, although a somewhat larger intersubject variability was found.