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Pyroglutamic acid improves the age associated memory impairment
Author(s) -
Grioli S.,
Lomeo C.,
Quattropani MC,
Spignoli G.,
Villardita C.
Publication year - 1990
Publication title -
fundamental and clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.655
H-Index - 73
eISSN - 1472-8206
pISSN - 0767-3981
DOI - 10.1111/j.1472-8206.1990.tb00485.x
Subject(s) - pyroglutamic acid , medicine , memory impairment , gerontology , psychiatry , chemistry , biochemistry , amino acid , cognition
Summary— Pyroglutamic acid (PCA) was compared with placebo in a randomized, double blind trial for assessing its efficacy in treating memory deficits in 40 aged subjects. Twenty subjects were treated with PCA and 20 with placebo over a period of 60 d. Memory functions were evaluated at baseline and after 60 d of treatment by means of a battery made up of 6 memory tasks. The results suggest that PCA is effective in improving some verbal memory functions in subjects affected by age‐related memory decline.