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Tissue distribution of dextromoramide in the rat
Author(s) -
Kintz P.,
Tracqui A.,
Mangin P.,
Lugnier AA,
Chaumont AJ
Publication year - 1990
Publication title -
fundamental and clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.655
H-Index - 73
eISSN - 1472-8206
pISSN - 0767-3981
DOI - 10.1111/j.1472-8206.1990.tb00484.x
Subject(s) - distribution (mathematics) , tissue distribution , intraperitoneal injection , liver tissue , pharmacology , chemistry , biology , medicine , endocrinology , mathematics , mathematical analysis
Summary— The tissue distribution of dextromoramide was studied in rats after the intraperitoneal injection of 0.2 mg/kg of the drug. The pattern of distribution was similar at 15, 30, 60 and 90 min, with the highest concentrations being found in the liver and the myocardium, while other organs were not able to concentrate dextromoramide.